Acne during pregnancy and lactation
How can I do?
Recently, I have been diagnosed with patients with acne during pregnancy and lactating acne. Because I am also a baby, I know that it is not easy to be a mother, so I stay up late to 3 or four in the morning (I have to be born with acne), and I wrote this.Small article.People often say that they are pregnant for the secondary disease. Although this statement is not necessarily right, it is really difficult to get pregnant in October., Take a small step every day, feel what is faltering.
Women are really great. Not only must they bear the suffering of October in October, but also giving children a breast feed on the child after unloading, but also during pregnancy and feeding, whether it is a cold, fever or headache and diarrhea, they will endure and endure again and endure.Unless you can’t help it, you will go to the hospital for consultation.Come, let go of your mobile phone and like our great women.At the same time, we call on our male compatriots, whether it is Double 11 or Double 12, take the initiative to help his wife fill up the shopping cart.There is a shopping cart, a hope.
Nonsense is far away!
Please forgive Yun’s funny heart.
What should I do if women have acne during the baby and breastfeeding?
Come, let your elder man help you choose one,
It really doesn’t work, throw a small paper, grab it.
Regardless of it, it will be fine by yourself;
That must be detox;
Consult the professional dermatologist;
Choose A or B
Click on the blank part below to get interpretation
If you choose A or B, please strictly control the economic export control in the future. In the future, 200 yuan per month for pocket money per month.
Click on the blank part below to get interpretation
If you choose C, a typical face value control, this kind of man is actually unreliable and easy to spend. As long as he goes out, you must send positioning at any time.
Just kidding, kidding!
People generally think that acne is a cosmetic problem. During pregnancy and lactation, whether it is a doctor or a patient, worrying about the serious consequences of the drug may cause the teratogenictreat.There are many women bumping around, flipping on Weibo, watching strategies, and hoping to skin care products, but can you imagine that helplessness?Spring goes to spring again, acne is still there.
Women during pregnancy and lactation are not human?Do you really have to endure the spicy hand of acne?In fact, it can be treated.
When deciding to treat acne during pregnancy or breastfeeding, and choosing specific drugs, you should carefully consider the severity of acne grading. You must know which medicines can be used and which tigers cannot be touched!
Let’s take a look at topical drugs:
Commonly used topical antibiotics include: erythromycin, clinithromycin, and metronidazole (FDA classified as category B medication). It can be used safely during pregnancy and lactation, but it is necessary to realize that the use of antibiotic drugs for a long time should be realizedThere may be risks of drug resistance. It is recommended to use it with peroxylzyl to reduce drug tolerance during breastfeeding.
2. Peroxylzolic gel
In addition to antibacteriality (C), peroxyl gel (C) has the effect of dissolving acne.It is not recommended during pregnancy, but it is relatively safe during breastfeeding, because the amount of absorption is very small.
3, salicylic acid
Salmonic acid (C) has been used as a non -prescription skin drug for many years (many skin care products have also been added with salicylic acid), and there are no deformed reports.Its oral form aspirin, which is used in low -dose to prevent pregnancy premature eclampsia, which affirms its safety.In babies fed in breast milk, theoretical risk of reye syndrome is presented to the reye syndrome, but local salicylic acid is unlikely to occur due to the small skin absorption, especially if it is limited to the use of small areas of the skin.
4. Ren Er acid
Ren di kinds is a natural di carboxylic acid, which has antibacterial, acne dissolving and mild anti -inflammatory properties.Ren dietic acid also has a inhibitory effect on tyrosinase, so it can improve the inflammatory pigmentation caused by acne.Ren diexin is classified as a category B by FDA. Because animal research shows that there is no teratogenicity, but there is no clinical data about human body, it can be used during pregnancy and breastfeeding.
5. Deminic acid drugs
Vitamin and Adapolin were classified as a pregnancy category C by FDA, but he belonged to Class X.There are controversy on reporting on the safety of local exterior naphic acid drugs for pregnant women or breastfeeding women.It is reported that the use of such drugs that cause congenital malformations (Autret et al., 1997, Lipson et al., 1993, LOUREIRO et al., 2005, Navarre-Belhassen et al., 1998, Panchaud et al, 2012, Selcen et al, 2000), butThese events may be coincidental.However, a large -scale observation and forward -looking research on a large -scale observation of 235 women in early pregnancy was compared with 444 women in the control group. No natural abortion rate and mild or major birth defects were found.Panchaud et al., 2012).There is no consensus on the safety of vitaminic acid drugs during pregnancy (Van Hoogdalem, 1998).But for safety reasons, it is recommended not to use such topical drugs during pregnancy.
Victoria A and Ada Palin gel in small area during lactation is relatively safe, because the system absorption is very low, but the safety of his Zarotine gel in breastfeeding is not clear, so avoid it avoideduse.
If local medication is not effective and acne is relatively heavy, you can consider oral drugs.Commonly used oral drugs for acne therapy include: antibiotics, hormone therapy (snails, contraceptives, etc.), vitamin acid drugs, but which drugs are relatively safe during pregnancy and lactation?
I. Tetthian and derivatives
Tethellian drugs, including Minisyin, Doxin, and tetracycline, are considered first -line treatment of patients with medium -weight inflammatory acne.It can cause discoloration of teeth and bones.However, there is no conclusive evidence that early use of early pregnancy is related to major birth defects (Kong and Tey, 2013, MEREDITH and ORMEROD, 2013).It has been reported that the female hepatic toxicity cases caused by tetracycline drugs (Hale and POMERANZ, 2002, Rothman and POCHI, 1988, Wenk, etc.) in the use of tetracycline drugs in advanced pregnancy have been reported.
Second, different dimension A sour capsules
The use of a handle in the acne industry, the use of oral vitamin A acid during pregnancy is absolutely contraindicated (FDA is classified as a pregnancy X drug), and the different vitamin A acid has teratogenicity (has nothing to do with dosage), which can lead to natural abortion and endangering.The serious congenital deformity of life.Early pregnancy -induced embryo diseases include the malformations of the skull facial, heart, thymus, and central nervous system.It has not been found that men’s use of alien A acid can cause fetal abnormalities.Due to these serious influence, as a doctor, women who have informed the treatment of different -dimensional A acid treatment, one month before the treatment of different -dimensional A acid treatment, during the treatment period and within one month after treatment, all women with fertility potential must choose and guarantee to ensure thatIt is important to perform two contraceptive measures. Remember.
Oral erythromycin is classified as a pregnancy category B by FDA. In fact, erythromycin is more commonly used to treat other infections during pregnancy.Although erythromycin is considered safe during pregnancy, there are reports about fetal heart malformation (Kallen et al., 2005), long-term use is related to the hepatic toxicity of 10-15 % of pregnancy patients (Hale and POMERANZ, 2002, 2002,, 2002,McCormack et al., 1977).Many patients with side effects that cannot be tolerated. In addition, acne propadate is often resistant to the drug, so treatment is often caused.
Like erythromycin, it is a category B medication during pregnancy. Compared with erythromycin, the tolerance is slightly better. Relatively speaking, the risk of drug resistance is smaller, but in fact, because bacteria are on this drug to this drugThe incidence of antibiotics has continued to increase, so Azithromycin is generally not used as a conventional treatment plan for acne.
5. Cefbal antibiotics
Peloxycin and cephalosporin are safe during pregnancy and breastfeeding (Hale and POMERANZ, 2002), however, they are rarely used to treat acne.The potential disadvantages of cephalosporin antibiotics include: the sebaceous gland units cannot be infiltrated due to hydrophilicity, and here is the part of acne specifically; and the emergence of methamphetamine Golden Polyxibacteria can be promoted.Compared with macromone (erythromycin and Azithromycin), its curative effect is poor.
6. Commonly used hormone drugs
Commonly used hormone drugs are screw (C), oral contraceptives (X), and cyclopypene ketones (X).These antiatrox drugs should be avoided during pregnancy and breastfeeding, because they are related to the feminine of the urethral cracks and the feminine of male fetuses.There is also a high incidence of Tang’s syndrome in the use of oral contraceptives in early pregnancy.It should be avoided during breastfeeding. There are two reasons: According to reports, estrogen in oral contraceptive pills may reduce milk production, and there is a theoretical risk of fetal feminine, especially the ability of newborn to metabolize additional hormones is weak.Essence
Of course, in addition to these topical drugs, you can also cooperate with phototherapy. For example, red and blue light irradiation therapy is currently believed that blue light and red light absorbed acne by absorbing light produced by acne pupacol.Gravine can absorb light with a wavelength of 400-700nm, and the light absorption efficiency of the light absorption of about 410nm (in the blue light area of absorbing spectrum) is the highest.Due to exposure to light, pyrine is activated, which causes oxygen free radicals and bacterial death.The intensity of red light to activate pheasin is weaker than Blu -ray, but red light can penetrate into the skin deeper.Because it uses a specific, safe wavelength light, it is generally believed that Blu -ray and red light are safe for pregnant women and lactating women.The use of Blu -ray therapy to treat neonatal hyperbilotin ledin (neonatal jaundice) further confirmed its security (McDonagh AF, Lightner Da. ‘Like A shrivelled bloode orange’ -bilirubin, jaundice, and Phototherapy. Pediatri. cs. 1985;75 (3): 443–55.).
For pregnancy and lactation acne, it is recommended to use local topical drugs as first -line treatment solutions: antibiotics (erythromycin, clinithromycin, metronidazole), 20%die acidic acid.The peroxylzyl is category C in the classification of pregnancy drugs, but it can be used safely during breastfeeding, and at the same time, it can be treated with red and blue light.Of course, if the acne is indeed heavy and the external drug is not controlled, you can consider orally oral ectodine antibiotics, but you need to take medicine under the guidance of a professional doctor.
Figures: common drugs and treatment plans for acne, classification and suggestions in the safety level of pregnancy and lactation during pregnancy and lactation:
△ Click the picture above to view the big picture
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Author: Li Yun
(Dr. Li Yun has opened a consulting service in Dr. "Dr. Lilac")
Some pictures are from the Internet. If you have copyright issues, please contact us in time!
Yang Xichuan, a doctor of medicine, professor, chief physician, deputy director of the dermatology department of Southwest Hospital of the Army Military Medical University.He is the deputy chairman of the Dermatology Committee of the Chinese Medical Association Dermatology Branch and the leader of the Derivation of the Dermatology Committee and the leader of the Difficulty Disease Research Team, a member of the Dermatology Branch of the Chinese Medical Association Dermatology Branch, and the Mao Hair Study Group of the Chinese and Western Medicine Society of Chinese and Western MedicineMember, member of the Chongqing Medical Association Dermatology Branch Committee, member of the Chongqing Municipal Dermatology Specialist Committee, etc., is the "Chinese Dermatology Magazine", "International Dermatology Magazine", "Practical Skin Disease Magazine" and "Skin Skin"Editorial Committee of the Magazine of Diseases and STDs.Presided over 5 projects on the National Natural Science Foundation of China.The editor -in -chief and editor -in -chief have 14 monographs, published 75 papers with the first and communication authors, of which 16 are included in SCI.Rong stand on the individual three -class merit twice.